Virions of primary human immunodeficiency virus type 1 isolates resistant to soluble CD4 (sCD4) neutralization differ in sCD4 binding and glycoprotein gp120 retention from sCD4-sensitive isolates.

Primary isolates of human immunodeficiency virus type 1 (HIV-1) are much less sensitive to neutralization by soluble CD4 (sCD4) and sCD4-immunoglobulin (Ig) chimeras (CD4-IgG) than are HIV-1 strains adapted to growth in cell culture. We demonstrated that there are significant reductions (10- to 30-f...

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Εκδόθηκε σε:	J Virol
Κύριοι συγγραφείς:	Moore, J P, McKeating, J A, Huang, Y X, Ashkenazi, A, Ho, D D
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	American Society for Microbiology (ASM) 1992
Θέματα:	Research Article
Διαθέσιμο Online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC238280/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1727487/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.66.1.235-243.1992
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