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Distinct mechanisms of splicing regulation in vivo by the Drosophila protein Sex-lethal

The protein Sex-lethal (SXL) controls pre-mRNA splicing of two genes involved in Drosophila sex determination: transformer (tra) and the Sxl gene itself. Previous in vitro results indicated that SXL antagonizes the general splicing factor U2AF(65) to regulate splicing of tra. In this report, we have...

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Autori principali: Granadino, Begoña, Penalva, Luiz O. F., Green, Michael R., Valcárcel, Juán, Sánchez, Lucas
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences of the USA 1997
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC23823/
https://ncbi.nlm.nih.gov/pubmed/9207093
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