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Molecular determinants of macrophage tropism and viral persistence: importance of single amino acid changes in the polymerase and glycoprotein of lymphocytic choriomeningitis virus.

This study documents that the immunosuppressive lymphocytic choriomeningitis virus (LCMV) variant, clone 13, shows a specific predilection for enhanced infection of macrophages both in vitro and in vivo and that single amino acid changes in the viral polymerase and glycoprotein are responsible for m...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:J Virol
Asıl Yazarlar: Matloubian, M, Kolhekar, S R, Somasundaram, T, Ahmed, R
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology (ASM) 1993
Konular:
Online Erişim:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC238198/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7693969/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.67.12.7340-7349.1993
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