Genetic analysis of in vivo-selected viral variants causing chronic infection: importance of mutation in the L RNA segment of lymphocytic choriomeningitis virus.

Viral variants with different biological properties are present in the central nervous systems (CNS) and lymphoid tissues of mice persistently infected with lymphocytic choriomeningitis virus (LCMV). Viral isolates from the CNS are similar to the original Armstrong LCMV strain and induce potent viru...

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Autors principals: Ahmed, R, Simon, R S, Matloubian, M, Kolhekar, S R, Southern, P J, Freedman, D M
Format: Artigo
Idioma:Inglês
Publicat: 1988
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC253451/
https://ncbi.nlm.nih.gov/pubmed/3261347
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