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Increased spacing between Sp1 and TATAA renders human immunodeficiency virus type 1 replication defective: implication for Tat function.

Expression of the human immunodeficiency virus type 1 (HIV-1) is strongly activated by Tat. The proper action of Tat requires three elements: TATAA, TAR, and upstream motifs in the HIV-1 long terminal repeat. We show here that the correct spatial arrangement among Tat, Sp1, and TATAA crucially influ...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:J Virol
Päätekijät: Huang, L M, Jeang, K T
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology (ASM) 1993
Aiheet:
Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC238151/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8230415/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.67.12.6937-6944.1993
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