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In vitro and in vivo binding of human immunodeficiency virus type 1 Tat protein and Sp1 transcription factor.

Recent genetic experiments have suggested that tat transactivation of the human immunodeficiency virus type 1 (HIV-1) long terminal repeat requires functional upstream enhancer sequences--Sp1 sites, in particular. In these experiments, HeLa cell nuclear extracts were passed over affinity matrices co...

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Bibliographic Details
Main Authors: Jeang, K T, Chun, R, Lin, N H, Gatignol, A, Glabe, C G, Fan, H
Format: Artigo
Language:Inglês
Published: 1993
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC238044/
https://ncbi.nlm.nih.gov/pubmed/7690421
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