Fas-induced apoptosis of T cells occurs independently of ceramide generation

The Fas receptor is one of a number of important physiological inducers of programmed cell death (apoptosis). Current models for regulation of this process involve rapid conversion of sphingomyelin to ceramide by cellular sphingomyelinases. Induced changes in cellular levels of such sphingosine-base...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Watts, Julian D., Gu, Ming, Polverino, Anthony J., Patterson, Scott D., Aebersold, Ruedi
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1997
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC23814/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9207084/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.14.7292
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