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Phosphatidylcholine hydrolysis activates NF-kappa B and increases human immunodeficiency virus replication in human monocytes and T lymphocytes.

We have tested whether breakdown of phosphatidylcholine (PC) initiated by exogenous addition of a PC-specific phospholipase C (PC-PLC) from Bacillus cereus or by endogenous overexpression of PC-PLC induces functional activation of NF-kappa B and increases human immunodeficiency virus (HIV) enhancer...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Arenzana-Seisdedos, F, Fernandez, B, Dominguez, I, Jacqué, J M, Thomas, D, Diaz-Meco, M T, Moscat, J, Virelizier, J L
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1993
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC238097/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8411362/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.67.11.6596-6604.1993
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