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Distinct roles for E2F proteins in cell growth control and apoptosis

E2F transcription activity is composed of a family of heterodimers encoded by distinct genes. Through the overproduction of each of the five known E2F proteins in mammalian cells, we demonstrate that a large number of genes encoding proteins important for cell cycle regulation and DNA replication ca...

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Autori principali: DeGregori, James, Leone, Gustavo, Miron, Alexander, Jakoi, Laszlo, Nevins, Joseph R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences of the USA 1997
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC23805/
https://ncbi.nlm.nih.gov/pubmed/9207076
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