Features of the adeno-associated virus origin involved in substrate recognition by the viral Rep protein.

We previously demonstrated that the adeno-associated virus (AAV) Rep68 and Rep78 proteins are able to nick the AAV origin of DNA replication at the terminal resolution site (trs) in an ATP-dependent manner. Using four types of modified or mutant substrates, we now have investigated the substrate req...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Snyder, R O, Im, D S, Ni, T, Xiao, X, Samulski, R J, Muzyczka, N
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1993
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC238031/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8396670/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.67.10.6096-6104.1993
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