Features of the adeno-associated virus origin involved in substrate recognition by the viral Rep protein.

We previously demonstrated that the adeno-associated virus (AAV) Rep68 and Rep78 proteins are able to nick the AAV origin of DNA replication at the terminal resolution site (trs) in an ATP-dependent manner. Using four types of modified or mutant substrates, we now have investigated the substrate req...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Snyder, R O, Im, D S, Ni, T, Xiao, X, Samulski, R J, Muzyczka, N
Format: Artigo
Langue:Inglês
Publié: 1993
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC238031/
https://ncbi.nlm.nih.gov/pubmed/8396670
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