Influence of epitope polarity and adjuvants on the immunogenicity and efficacy of a synthetic peptide vaccine against Semliki Forest virus.

The antibody response to a previously defined B-cell epitope of Semliki Forest virus (SFV) was investigated in male BALB/c (H-2d) mice. The B-cell epitope, located at amino acid positions 240 to 255 of the E2 protein, was linked to an H-2d-restricted T-helper cell epitope of SFV located at positions...

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Bibliographic Details
Published in:J Virol
Main Authors: Fernández, I M, Snijders, A, Benaissa-Trouw, B J, Harmsen, M, Snippe, H, Kraaijeveld, C A
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1993
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC238002/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7690411/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.67.10.5843-5848.1993
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