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cdc2 phosphorylation of threonine 124 activates the origin-unwinding functions of simian virus 40 T antigen.

Phosphorylation of simian virus 40 (SV40) T antigen on threonine 124 activates viral DNA replication in vivo and in vitro. We have manipulated the modification of T-antigen residue 124 both genetically and biochemically and have investigated individual replication functions of T antigen under condit...

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Udgivet i:J Virol
Principais autores: McVey, D, Ray, S, Gluzman, Y, Berger, L, Wildeman, A G, Marshak, D R, Tegtmeyer, P
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1993
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC237918/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8394445/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.67.9.5206-5215.1993
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