Immunochemical analysis of the gp120 surface glycoprotein of human immunodeficiency virus type 1: probing the structure of the C4 and V4 domains and the interaction of the C4 domain with the V3 loop.

We have probed the structure of the C4 and V3 domains of human immunodeficiency virus type 1 gp120 by immunochemical techniques. Monoclonal antibodies (MAbs) recognizing an exposed gp120 sequence, (E/K)VGKAMYAPP, in C4 were differentially sensitive to denaturation of gp120, implying a conformational...

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Pubblicato in:	J Virol
Autori principali:	Moore, J P, Thali, M, Jameson, B A, Vignaux, F, Lewis, G K, Poon, S W, Charles, M, Fung, M S, Sun, B, Durda, P J
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1993
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC237865/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7687303/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.67.8.4785-4796.1993
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