Immunochemical analysis of the gp120 surface glycoprotein of human immunodeficiency virus type 1: probing the structure of the C4 and V4 domains and the interaction of the C4 domain with the V3 loop.

We have probed the structure of the C4 and V3 domains of human immunodeficiency virus type 1 gp120 by immunochemical techniques. Monoclonal antibodies (MAbs) recognizing an exposed gp120 sequence, (E/K)VGKAMYAPP, in C4 were differentially sensitive to denaturation of gp120, implying a conformational...

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Detalhes bibliográficos
Main Authors: Moore, J P, Thali, M, Jameson, B A, Vignaux, F, Lewis, G K, Poon, S W, Charles, M, Fung, M S, Sun, B, Durda, P J
Formato: Artigo
Idioma:Inglês
Publicado em: 1993
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC237865/
https://ncbi.nlm.nih.gov/pubmed/7687303
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