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ICP4, the major transcriptional regulatory protein of herpes simplex virus type 1, forms a tripartite complex with TATA-binding protein and TFIIB.

The ICP4 protein of herpes simplex virus can either increase or decrease the rate of transcription mediated by RNA polymerase II, depending on the target promoter. The interplay of DNA-protein and protein-protein contacts determining ICP4 function has yet to be characterized, and consequently the mo...

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Detalles Bibliográficos
Publicado en:J Virol
Autores principales: Smith, C A, Bates, P, Rivera-Gonzalez, R, Gu, B, DeLuca, N A
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 1993
Materias:
Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC237853/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8392607/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.67.8.4676-4687.1993
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