ICP4, the major transcriptional regulatory protein of herpes simplex virus type 1, forms a tripartite complex with TATA-binding protein and TFIIB.

The ICP4 protein of herpes simplex virus can either increase or decrease the rate of transcription mediated by RNA polymerase II, depending on the target promoter. The interplay of DNA-protein and protein-protein contacts determining ICP4 function has yet to be characterized, and consequently the mo...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Smith, C A, Bates, P, Rivera-Gonzalez, R, Gu, B, DeLuca, N A
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1993
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC237853/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8392607/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.67.8.4676-4687.1993
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