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Recombinant human hepatitis B virus reverse transcriptase is active in the absence of the nucleocapsid or the viral replication origin, DR1.

The double-stranded DNA genome of hepatitis B virus (HBV) is reverse transcribed from the viral pregenome RNA template by a virally encoded reverse transcriptase enzyme (RT) that possesses both priming and elongation activities. Prior efforts have failed to express an active form of HBV RT outside t...

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Detalles Bibliográficos
Publicado en:J Virol
Autores principales: Seifer, M, Standring, D N
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 1993
Materias:
Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC237835/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7687299/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.67.8.4513-4520.1993
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