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Recombinant human hepatitis B virus reverse transcriptase is active in the absence of the nucleocapsid or the viral replication origin, DR1.

The double-stranded DNA genome of hepatitis B virus (HBV) is reverse transcribed from the viral pregenome RNA template by a virally encoded reverse transcriptase enzyme (RT) that possesses both priming and elongation activities. Prior efforts have failed to express an active form of HBV RT outside t...

Ausführliche Beschreibung

Gespeichert in:
Bibliografische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Seifer, M, Standring, D N
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 1993
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC237835/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7687299/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.67.8.4513-4520.1993
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