Molecular characterization of mouse-virulent poliovirus type 1 Mahoney mutants: involvement of residues of polypeptides VP1 and VP2 located on the inner surface of the capsid protein shell.

Most poliovirus (PV) strains, including PV PV-1/Mahoney, are unable to cause paralysis in mice. Determinants for restriction of PV-1/Mahoney in mice have been identified by manipulating PV-1 cDNA and located on the viral capsid protein VP1. These determinants consist of a highly exposed amino acid s...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Couderc, T, Hogle, J, Le Blay, H, Horaud, F, Blondel, B
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1993
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC237745/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8389907/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.67.7.3808-3817.1993
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