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Sequence homology and microhomology dominate chromosomal double-strand break repair in African trypanosomes
Genetic diversity in fungi and mammals is generated through mitotic double-strand break-repair (DSBR), typically involving homologous recombination (HR) or non-homologous end joining (NHEJ). Microhomology-mediated joining appears to serve a subsidiary function. The African trypanosome, a divergent p...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Oxford University Press
2008
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2377438/ https://ncbi.nlm.nih.gov/pubmed/18334531 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn104 |
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