Bile Acid Exposure Up-regulates Tuberous Sclerosis Complex 1/Mammalian Target of Rapamycin Pathway in Barrett’s-Associated Esophageal Adenocarcinoma

Barrett’s esophagus, a columnar metaplasia of the lower esophagus epithelium related to gastroesophageal reflux disease, is the strongest known risk factor for the development of esophageal adenocarcinoma (EAC). Understanding the signal transduction events involved in esophageal epithelium carcinoge...

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Hauptverfasser: Yen, Chia-Jui, Izzo, Julie G., Lee, Dung-Fang, Guha, Sushovan, Wei, Yongkun, Wu, Tsung-Teh, Chen, Chun-Te, Kuo, Hsu-Ping, Hsu, Jung-Mao, Sun, Hui-Lung, Chou, Chao-Kai, Buttar, Navtej S., Wang, Kenneth K., Huang, Peng, Ajani, Jaffer, Hung, Mien-Chie
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2377413/
https://ncbi.nlm.nih.gov/pubmed/18413730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-07-5460
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