Bile Acid Exposure Up-regulates Tuberous Sclerosis Complex 1/Mammalian Target of Rapamycin Pathway in Barrett’s-Associated Esophageal Adenocarcinoma

Barrett’s esophagus, a columnar metaplasia of the lower esophagus epithelium related to gastroesophageal reflux disease, is the strongest known risk factor for the development of esophageal adenocarcinoma (EAC). Understanding the signal transduction events involved in esophageal epithelium carcinoge...

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Bibliografiske detaljer
Main Authors: Yen, Chia-Jui, Izzo, Julie G., Lee, Dung-Fang, Guha, Sushovan, Wei, Yongkun, Wu, Tsung-Teh, Chen, Chun-Te, Kuo, Hsu-Ping, Hsu, Jung-Mao, Sun, Hui-Lung, Chou, Chao-Kai, Buttar, Navtej S., Wang, Kenneth K., Huang, Peng, Ajani, Jaffer, Hung, Mien-Chie
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2377413/
https://ncbi.nlm.nih.gov/pubmed/18413730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-07-5460
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