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Gangliosides and Nogo Receptors Independently Mediate Myelin-associated Glycoprotein Inhibition of Neurite Outgrowth in Different Nerve Cells

In the injured nervous system, myelin-associated glycoprotein (MAG) on residual myelin binds to receptors on axons, inhibits axon outgrowth, and limits functional recovery. Conflicting reports identify gangliosides (GD1a and GT1b) and glycosylphosphatidylinositol-anchored Nogo receptors (NgRs) as ex...

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Detalhes bibliográficos
Main Authors: Mehta, Niraj R., Lopez, Pablo H. H., Vyas, Alka A., Schnaar, Ronald L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2377359/
https://ncbi.nlm.nih.gov/pubmed/17640868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M704055200
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