Gangliosides are functional nerve cell ligands for myelin-associated glycoprotein (MAG), an inhibitor of nerve regeneration

Myelin-associated glycoprotein (MAG) binds to the nerve cell surface and inhibits nerve regeneration. The nerve cell surface ligand(s) for MAG are not established, although sialic acid-bearing glycans have been implicated. We identify the nerve cell surface gangliosides GD1a and GT1b as specific fun...

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Detalles Bibliográficos
Main Authors: Vyas, Alka A., Patel, Himatkumar V., Fromholt, Susan E., Heffer-Lauc, Marija, Vyas, Kavita A., Dang, Jiyoung, Schachner, Melitta, Schnaar, Ronald L.
Formato: Artigo
Idioma:Inglês
Publicado: The National Academy of Sciences 2002
Assuntos:
Biological Sciences
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC123081/
https://ncbi.nlm.nih.gov/pubmed/12060784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.072211699
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