Pharmacological Inhibition of Nicotinamide Phosphoribosyltransferase/Visfatin Enzymatic Activity Identifies a New Inflammatory Pathway Linked to NAD

Nicotinamide phosphoribosyltransferase (NAMPT), also known as visfatin, is the rate-limiting enzyme in the salvage pathway of NAD biosynthesis from nicotinamide. Since its expression is upregulated during inflammation, NAMPT represents a novel clinical biomarker in acute lung injury, rheumatoid arth...

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Detalhes bibliográficos
Main Authors: Busso, Nathalie, Karababa, Mahir, Nobile, Massimo, Rolaz, Aline, Van Gool, Frédéric, Galli, Mara, Leo, Oberdan, So, Alexander, De Smedt, Thibaut
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2377336/
https://ncbi.nlm.nih.gov/pubmed/18493620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0002267
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