Comprehensive screening for antigens overexpressed on carcinomas via isolation of human mAbs that may be therapeutic

Although several murine mAbs that have been humanized became useful therapeutic agents against a few malignancies, therapeutic Abs are not yet available for the majority of the human cancers because of our lack of knowledge of which antigens (Ags) can become useful targets. In the present study we e...

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Autors principals: Kurosawa, Gene, Akahori, Yasushi, Morita, Miwa, Sumitomo, Mariko, Sato, Noriko, Muramatsu, Chiho, Eguchi, Keiko, Matsuda, Kazuki, Takasaki, Akihiko, Tanaka, Miho, Iba, Yoshitaka, Hamada-Tsutsumi, Susumu, Ukai, Yoshinori, Shiraishi, Mamoru, Suzuki, Kazuhiro, Kurosawa, Maiko, Fujiyama, Sally, Takahashi, Nobuhiro, Kato, Ryoichi, Mizoguchi, Yoshikazu, Shamoto, Mikihiro, Tsuda, Hiroyuki, Sugiura, Mototaka, Hattori, Yoshinobu, Miyakawa, Shuichi, Shiroki, Ryoichi, Hoshinaga, Kiyotaka, Hayashi, Nobuhiro, Sugioka, Atsushi, Kurosawa, Yoshikazu
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2008
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2377314/
https://ncbi.nlm.nih.gov/pubmed/18474866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0712202105
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