Comprehensive screening for antigens overexpressed on carcinomas via isolation of human mAbs that may be therapeutic

Although several murine mAbs that have been humanized became useful therapeutic agents against a few malignancies, therapeutic Abs are not yet available for the majority of the human cancers because of our lack of knowledge of which antigens (Ags) can become useful targets. In the present study we e...

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Main Authors: Kurosawa, Gene, Akahori, Yasushi, Morita, Miwa, Sumitomo, Mariko, Sato, Noriko, Muramatsu, Chiho, Eguchi, Keiko, Matsuda, Kazuki, Takasaki, Akihiko, Tanaka, Miho, Iba, Yoshitaka, Hamada-Tsutsumi, Susumu, Ukai, Yoshinori, Shiraishi, Mamoru, Suzuki, Kazuhiro, Kurosawa, Maiko, Fujiyama, Sally, Takahashi, Nobuhiro, Kato, Ryoichi, Mizoguchi, Yoshikazu, Shamoto, Mikihiro, Tsuda, Hiroyuki, Sugiura, Mototaka, Hattori, Yoshinobu, Miyakawa, Shuichi, Shiroki, Ryoichi, Hoshinaga, Kiyotaka, Hayashi, Nobuhiro, Sugioka, Atsushi, Kurosawa, Yoshikazu
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2008
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2377314/
https://ncbi.nlm.nih.gov/pubmed/18474866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0712202105
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