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A three-nucleotide insertion in the H stem-loop of the 5' untranslated region of Theiler's virus attenuates neurovirulence.

The highly structured 5' untranslated region (5' UTR) of Theiler's murine encephalomyelitis virus is involved in cap-independent translation of the viral RNA. Previously, we reported that the bicistronic mRNA chloramphenicol acetyltransferase-5' UTR-luciferase (Luc) efficiently expressed Luc both in...

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Bibliographic Details
Published in:J Virol
Main Authors: Bandyopadhyay, P K, Pritchard, A, Jensen, K, Lipton, H L
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1993
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC237727/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7684472/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.67.6.3691-3695.1993
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