Effect of linker insertion mutations in the human immunodeficiency virus type 1 gag gene on activation of viral protease expressed in bacteria.

We have expressed the human immunodeficiency virus type 1 (HIV-1) protease (PR) in bacteria as a Gag-PR polyprotein (J. Luban and S.P. Goff, J. Virol. 65:3203-3212, 1991). The protein displays enzymatic activity, cleaving the Gag polyprotein precursor Pr55gag to the expected products. The PR enzyme...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Virol
Auteurs principaux: Luban, J, Lee, C, Goff, S P
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 1993
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC237714/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8497070/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.67.6.3630-3634.1993
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