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Aldose reductase inhibition prevents endotoxin-induced uveitis in rats
PURPOSE: The purpose of the present study was to elucidate the role of the polyol pathway enzyme, aldose reductase (AR) in the mediation of ocular inflammation in rat model of endotoxin-induced uveitis (EIU). METHODS: EIU was induced by a subcutaneous injection of lipopolysaccharide (LPS) (200 μg) i...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2377062/ https://ncbi.nlm.nih.gov/pubmed/17898287 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.07-0485 |
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