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Aldose reductase inhibition prevents endotoxin-induced uveitis in rats

PURPOSE: The purpose of the present study was to elucidate the role of the polyol pathway enzyme, aldose reductase (AR) in the mediation of ocular inflammation in rat model of endotoxin-induced uveitis (EIU). METHODS: EIU was induced by a subcutaneous injection of lipopolysaccharide (LPS) (200 μg) i...

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Hlavní autoři: Yadav, Umesh C. S., Srivastava, Satish K., Ramana, Kota V.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2007
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2377062/
https://ncbi.nlm.nih.gov/pubmed/17898287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.07-0485
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