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Structural basis for viral late domain binding to Alix
The modular protein Alix is a central node in endosomal-lysosomal trafficking and the budding of HIV-1. The Gag p6 protein of HIV-1 contains a LYPX(n)LXXL motif that is required for Alix-mediated budding and binds to a region of Alix spanning residues 360-702. The structure of this fragment of Alix...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2377018/ https://ncbi.nlm.nih.gov/pubmed/17277784 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb1203 |
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