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Analysis of human prostate cancers and cell lines for mutations in the TP53 and KLF6 tumour suppressor genes

A recent report suggests that the KLF6 gene encoding the Krüppel-like factor 6 protein is a frequently mutated, putative tumour suppressor gene in prostate cancer. The aims of the present study were to confirm these initial findings by determining the frequency of exon2 KLF6 mutations in a cohort of...

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Autori principali: Mühlbauer, K-R, Gröne, H-J, Ernst, T, Gröne, E, Tschada, R, Hergenhahn, M, Hollstein, M
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2376923/
https://ncbi.nlm.nih.gov/pubmed/12915879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6601164
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