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Large-Scale Overexpression and Purification of ADARs from Saccharomyces cerevisiae for Biophysical and Biochemical Studies

Many biochemical and biophysical analyses of enzymes require quantities of protein that are difficult to obtain from expression in an endogenous system. To further complicate matters, native adenosine deaminases that act on RNA (ADARs) are expressed at very low levels, and overexpression of active p...

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Detalhes bibliográficos
Main Authors: Macbeth, Mark R., Bass, Brenda L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2376799/
https://ncbi.nlm.nih.gov/pubmed/17662848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0076-6879(07)24015-7
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