Crystallization and preliminary X-ray characterization of the Bacillus amyloliquefaciens YwrO enzyme

CB1954 is an anticancer prodrug that is currently in clinical trials coupled with the Escherichia coli flavoenzyme nitroreductase (NTR) for use in directed-enzyme prodrug therapy (DEPT). The NTR enzyme is responsible for the conversion of the prodrug into a cytotoxic agent. The bifunctional alkylati...

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Autori principali: AbuKhader, Majed M., Heap, John, De Matteis, Cristina I., Doughty, Stephen W., Minton, Nigel, Paoli, Max
Natura: Artigo
Lingua:Inglês
Pubblicazione: International Union of Crystallography 2007
Soggetti:
Crystallization Communications
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2376317/
https://ncbi.nlm.nih.gov/pubmed/17768344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309107035816
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