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Crystallization and preliminary X-ray characterization of the Bacillus amyloliquefaciens YwrO enzyme
CB1954 is an anticancer prodrug that is currently in clinical trials coupled with the Escherichia coli flavoenzyme nitroreductase (NTR) for use in directed-enzyme prodrug therapy (DEPT). The NTR enzyme is responsible for the conversion of the prodrug into a cytotoxic agent. The bifunctional alkylati...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
International Union of Crystallography
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2376317/ https://ncbi.nlm.nih.gov/pubmed/17768344 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309107035816 |
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