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A phase I trial to assess the pharmacology of the new oestrogen receptor antagonist fulvestrant on the endometrium in healthy postmenopausal volunteers

While tamoxifen use is associated with clear benefits in the treatment of hormone-sensitive breast cancer, it also exhibits partial oestrogen agonist activity that is associated with adverse events, including endometrial cancer. Fulvestrant (‘Faslodex’) is a new oestrogen receptor antagonist that do...

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Autors principals: Addo, S, Yates, R A, Laight, A
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2002
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2376292/
https://ncbi.nlm.nih.gov/pubmed/12454761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6600644
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