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A phase I trial to assess the pharmacology of the new oestrogen receptor antagonist fulvestrant on the endometrium in healthy postmenopausal volunteers

While tamoxifen use is associated with clear benefits in the treatment of hormone-sensitive breast cancer, it also exhibits partial oestrogen agonist activity that is associated with adverse events, including endometrial cancer. Fulvestrant (‘Faslodex’) is a new oestrogen receptor antagonist that do...

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Detalles Bibliográficos
Main Authors: Addo, S, Yates, R A, Laight, A
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2002
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2376292/
https://ncbi.nlm.nih.gov/pubmed/12454761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6600644
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