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Activated Nuclear Metabotropic Glutamate Receptor mGlu5 Couples to Nuclear G(q/11) Proteins to Generate Inositol 1,4,5-Trisphosphate-mediated Nuclear Ca(2+) Release
Recently we have shown that the metabotropic glutamate 5 (mGlu5) receptor can be expressed on nuclear membranes of heterologous cells or endogenously on striatal neurons where it can mediate nuclear Ca(2+) changes. Here, pharmacological, optical, and genetic techniques were used to show that upon ac...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Society for Biochemistry and Molecular Biology
2008
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2376237/ https://ncbi.nlm.nih.gov/pubmed/18337251 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M708551200 |
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