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Activated Nuclear Metabotropic Glutamate Receptor mGlu5 Couples to Nuclear G(q/11) Proteins to Generate Inositol 1,4,5-Trisphosphate-mediated Nuclear Ca(2+) Release

Recently we have shown that the metabotropic glutamate 5 (mGlu5) receptor can be expressed on nuclear membranes of heterologous cells or endogenously on striatal neurons where it can mediate nuclear Ca(2+) changes. Here, pharmacological, optical, and genetic techniques were used to show that upon ac...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Kumar, Vikas, Jong, Yuh-Jiin I., O'Malley, Karen L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2008
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2376237/
https://ncbi.nlm.nih.gov/pubmed/18337251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M708551200
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