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Apoptotic mechanisms in T47D and MCF-7 human breast cancer cells
To investigate the mechanisms underlying apoptosis in breast cancer cells, staurosporine was used as an apoptotic stimulus in the human breast cancer cell lines MCF-7 and T47D. Staurosporine induced dose and time dependent increases in DNA fragmentation which was abrogated by z-VAD-fmk. MCF-7 cells...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2002
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2376174/ https://ncbi.nlm.nih.gov/pubmed/12373608 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6600541 |
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