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Truncation of the cytoplasmic domain of the simian immunodeficiency virus envelope glycoprotein increases env incorporation into particles and fusogenicity and infectivity.

Growth of macaque simian immunodeficiency virus (SIVmac) in certain cloned human T-cell lines, such as HUT.78, selects for isolates containing a premature stop codon within the cytoplasmic domain of the transmembrane envelope glycoprotein. In contrast, propagation of virus in macaques or in their cu...

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Bibliografiska uppgifter
Huvudupphovsmän: Zingler, K, Littman, D R
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1993
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC237607/
https://ncbi.nlm.nih.gov/pubmed/8474176
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