Cytoplasmic domain truncation enhances fusion activity by the exterior glycoprotein complex of human immunodeficiency virus type 2 in selected cell types.

To investigate the glycoprotein determinants of viral cytopathology, we constructed chimeric env genes between a noncytopathic strain of human immunodeficiency virus type 2 (HIV-2), designated HIV-2/ST, and a highly fusogenic and cytopathic variant derived from this virus. Expression of the resultin...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Mulligan, M J, Yamshchikov, G V, Ritter, G D, Gao, F, Jin, M J, Nail, C D, Spies, C P, Hahn, B H, Compans, R W
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1992
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC241192/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1583738/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.66.6.3971-3975.1992
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