Cytoplasmic domain truncation enhances fusion activity by the exterior glycoprotein complex of human immunodeficiency virus type 2 in selected cell types.

To investigate the glycoprotein determinants of viral cytopathology, we constructed chimeric env genes between a noncytopathic strain of human immunodeficiency virus type 2 (HIV-2), designated HIV-2/ST, and a highly fusogenic and cytopathic variant derived from this virus. Expression of the resultin...

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Autores principales: Mulligan, M J, Yamshchikov, G V, Ritter, G D, Gao, F, Jin, M J, Nail, C D, Spies, C P, Hahn, B H, Compans, R W
Formato: Artigo
Lenguaje:Inglês
Publicado: 1992
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC241192/
https://ncbi.nlm.nih.gov/pubmed/1583738
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