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Culture of HepG2 liver cells on three dimensional polystyrene scaffolds enhances cell structure and function during toxicological challenge

Cultured cells are dramatically affected by the micro-environment in which they are grown. In this study, we have investigated whether HepG2 liver cells grown in three dimensional (3-D) cultures cope more effectively with the known cytotoxic agent, methotrexate, than their counterparts grown on trad...

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Detalhes bibliográficos
Main Authors: Bokhari, Maria, Carnachan, Ross J, Cameron, Neil R, Przyborski, Stefan A
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2375833/
https://ncbi.nlm.nih.gov/pubmed/17711423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-7580.2007.00778.x
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