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Physiological and toxicological transcriptome changes in HepG2 cells exposed to copper

Copper is an essential trace element; however, at supraphysiological levels, it can be extremely toxic. Microarray data from HepG2 cells exposed to 100, 200, 400, and 600 μM copper for 4, 8, 12 and 24 h were generated and analyzed. Principal components, K-means, and hierarchical clustering, interact...

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Detalhes bibliográficos
Main Authors: Song, Min Ok, Li, Jianying, Freedman, Jonathan H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3774564/
https://ncbi.nlm.nih.gov/pubmed/19549813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiolgenomics.00083.2009
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