Munc13-2(−/−) baseline secretion defect reveals source of oligomeric mucins in mouse airways

Since the airways of control mouse lungs contain few alcian blue/periodic acid–Schiff's (AB/PAS)+ staining ‘goblet’ cells in the absence of an inflammatory stimulus such as allergen sensitization, it was surprising to find that the lungs of mice deficient for the exocytic priming protein Munc13...

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Autores principales: Zhu, Yunxiang, Ehre, Camille, Abdullah, Lubna H, Sheehan, John K, Roy, Michelle, Evans, Christopher M, Dickey, Burton F, Davis, C William
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Science Inc 2008
Materias:
Respiratory
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2375724/
https://ncbi.nlm.nih.gov/pubmed/18258655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2007.149310
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