Hypothalamic input is required for development of normal numbers of thyrotrophs and gonadotrophs, but not other anterior pituitary cells in late gestation sheep

To evaluate the hypothalamic contribution to the development of anterior pituitary (AP) cells we surgically disconnected the hypothalamus from the pituitary (hypothalamo-pituitary disconnection, HPD) in fetal sheep and collected pituitaries 31 days later. Pituitaries (n = 6 per group) were obtained...

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Hlavní autoři: Szarek, Eva, Farrand, Kirsten, McMillen, I Caroline, Young, I Ross, Houghton, Daniel, Schwartz, Jeffrey
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Science Inc 2008
Témata:
Renal and Endocrine
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2375652/
https://ncbi.nlm.nih.gov/pubmed/18096603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2007.141523
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