Murine rotavirus genes encoding outer capsid proteins VP4 and VP7 are not major determinants of host range restriction and virulence.

Simian rotavirus (RRV) and murine rotavirus (EDIM-RW) differ dramatically in the oral inoculum required to cause diarrheal disease in neonatal mouse pups and in their ability to spread and cause disease in uninoculated littermates. A genetic approach was used to explore the molecular basis of these...

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Pubblicato in:	J Virol
Autori principali:	Broome, R L, Vo, P T, Ward, R L, Clark, H F, Greenberg, H B
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1993
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC237563/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8386262/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.67.5.2448-2455.1993
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