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Hyperpolarization-activated cyclic nucleotide-modulated ‘HCN’ channels confer regular and faster rhythmicity to beating mouse embryonic stem cells

The hyperpolarization-activated cation current (I(f)), and the hyperpolarization-activated cyclic nucleotide-modulated ‘HCN’ subunits that underlie it, are important components of spontaneous activity in the embryonic mouse heart, but whether they contribute to this activity in mouse embryonic stem...

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Autori principali: Qu, Yang, Whitaker, Gina M, Hove-Madsen, Leif, Tibbits, Glen F, Accili, Eric A
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2375615/
https://ncbi.nlm.nih.gov/pubmed/18033814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2007.144329
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