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Adrenergic regulation of a key cardiac potassium channel can contribute to atrial fibrillation: evidence from an I(Ks) transgenic mouse
Inherited gain-of-function mutations of genes coding for subunits of the heart slow potassium (I(Ks)) channel can cause familial atrial fibrillation (AF). Here we consider a potentially more prevalent mechanism and hypothesize that β-adrenergic receptor (β-AR)-mediated regulation of the I(Ks) channe...
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| Autores principales: | , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Blackwell Science Inc
2008
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2375578/ https://ncbi.nlm.nih.gov/pubmed/18006587 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2007.141333 |
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