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The E3L and K3L vaccinia virus gene products stimulate translation through inhibition of the double-stranded RNA-dependent protein kinase by different mechanisms.

Vaccinia virus has evolved multiple mechanisms to counteract the interferon-induced antiviral host cell response. Recently, two vaccinia virus gene products were shown to interfere with the activity of the double-stranded RNA-dependent protein kinase (PKR): the K3L gene product and the E3L gene prod...

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Detalles Bibliográficos
Publicado en:J Virol
Autores principales: Davies, M V, Chang, H W, Jacobs, B L, Kaufman, R J
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 1993
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC237544/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8094759/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.67.3.1688-1692.1993
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